Effect of Adjuvant Radiation Therapy on Urodynamic Parameters in Patients with Uterine Cervix Cancer

Hypothesis / aims of study Uterine cervix cancer is the second most common cancer among women and is one of the leading causes of cancer-related deaths in females [1]. Standard treatment for cervical cancer has been radical hysterectomy. Though many studies reported lower urinary tract dysfunction was the most common complication after radical pelvic surgery, there have been few studies on pathophysiologic changes related to urodynamics after adjuvant radiation therapy (RT). Many studies have reported RT can cause a smaller cystometric capacity and poor bladder compliance[2]. The aim of this study was (1) to assess the effect of radical hysterectomy on the storage function of the lower urinary tract and (2) to evaluate the impact of radiation therapy on postoperative bladder function using urodynamic parameters.